human XYLT2 shRNA silencing Adenovirus

Name 
Ad-h-XYLT2-shRNA
Cat No 
shADV-227943
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human XYLT2.

shADV-227943
Ad-h-XYLT2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human XYLT2 (xylosyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PXYLT2; SOS; XT-II; XT2; xylT-II
Description (Vector)
XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.
Gene ID
64132
Gene Name (Vector)
xylosyltransferase 2
Gene Symbol
XYLT2
HGNC ID
HGNC:15517
ORF Size (aa)
2598
ORF Size (bp)
2598 bp
RefSeq ID
NM_022167
RefSeq Synonyms
NM_022167, BC156444, BC052262,
Species
human
UniGene ID
Hs.463416

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.