human WIPF1 shRNA silencing Adenovirus

Name 
Ad-h-WIPF1-shRNA
Cat No 
shADV-227790
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human WIPF1.

shADV-227790
Ad-h-WIPF1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human WIPF1 (WAS/WASL interacting protein family member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
protein PRPL-2; PRPL-2; testicular tissue protein Li 226; WAS/WASL-interacting protein family member 1; WAS2; WASP-interacting protein; WASPIP; WIP; Wiskott-Aldrich syndrome protein interacting protein; Wiskott-Aldrich syndrome protein-interacting protein
Description (eCommerce)
WAS/WASL-interacting protein family member 1 (WIPF1) plays an important role in the organization of the actin cytoskeleton. WIPF1 binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the diseae [taken from NCBI Entrez Gene (Gene ID: 7456)].
Description (Vector)
WIPF1 encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.
Gene ID
7456
Gene Name (eCommerce)
WAS/WASL interacting protein family member 1
Gene Name (Vector)
WAS/WASL interacting protein family member 1
Gene Symbol
WIPF1
HGNC ID
HGNC:12736
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1077
Protein Name (eCommerce)
WAS/WASL-interacting protein family member 1
RefSeq ID
NM_003387
RefSeq Synonyms
NM_003387, NM_001077269, BC110288, BC002914,
Research Areas
Cytoskeleton,Fc Receptor Signaling,Immunology,Innate Immunity,SCF-KIT Signaling,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
signal_transduction,cell_biology,immunology,signal_transduction,stem_cell_biology,immunology
Species
human
Target Sentence
WAS/WASL-interacting protein family member 1 (WIPF1) plays an important role in the organization of the actin cytoskeleton. WIPF1 binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the diseae [taken from NCBI Entrez Gene (Gene ID: 7456)].
UniGene ID
Hs.128067
UniProt ID (eCommerce)
O43516

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.