human WDR45 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human WDR45.
shADV-227683
Ad-h-WDR45-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human WDR45 (WD repeat domain 45). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
JM5; NBIA4; NBIA5; WDRX1; WIPI-4; WIPI4
Description (Vector)
WDR45 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR45 has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.
Gene ID
11152
Gene Name (Vector)
WD repeat domain 45
Gene Symbol
WDR45
HGNC ID
HGNC:28912
ORF Size (aa)
1083
RefSeq ID
NM_007075
RefSeq Synonyms
NM_007075, NM_001029896, BC069206, BC003037, BC000464,
Species
human
UniGene ID
Hs.632807
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.