human WDR1 shRNA silencing Adenovirus

Name 
Ad-h-WDR1-shRNA
Cat No 
shADV-227639
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human WDR1.

shADV-227639
Ad-h-WDR1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human WDR1 (WD repeat domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
actin-interacting protein 1; AIP1; epididymis secretory protein Li 52; HEL-S-52; NORI-1; WD repeat-containing protein 1
Description (eCommerce)
WDR1 is a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. WDR1 may help induce the disassembly of actin filaments [taken from NCBI Entrez Gene (Gene ID: 9948)].
Description (Vector)
WDR1 encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
9948
Gene Name (eCommerce)
WD repeat domain 1
Gene Name (Vector)
WD repeat domain 1
Gene Symbol
WDR1
HGNC ID
HGNC:12754
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1821
ORF Size (bp)
1821 bp
Protein Name (eCommerce)
WD repeat-containing protein 1
RefSeq ID
NM_005112
RefSeq Synonyms
NM_017491, NM_005112, BC030541, BC002489, BC000201,
Research Areas
Cytoskeleton,Immunology,Neurobiology,T-cell Receptor Signaling
Research Areas (Faceted)
signal_transduction,cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
WDR1 is a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. WDR1 may help induce the disassembly of actin filaments [taken from NCBI Entrez Gene (Gene ID: 9948)].
UniGene ID
Hs.713658
UniProt ID (eCommerce)
O75083

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.