human VPS33A shRNA silencing Adenovirus

Name 
Ad-h-VPS33A-shRNA
Cat No 
shADV-227527
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human VPS33A.

shADV-227527
Ad-h-VPS33A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human VPS33A (VPS33A, CORVET/HOPS core subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
Gene ID
65082
Gene Name (Vector)
VPS33A, CORVET/HOPS core subunit
Gene Symbol
VPS33A
HGNC ID
HGNC:18179
ORF Size (aa)
1791
ORF Size (bp)
1791 bp
RefSeq ID
NM_022916
RefSeq Synonyms
NM_022916, BC016617,
Species
human
UniGene ID
Hs.592009

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.