human USP36 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human USP36.
shADV-227311
Ad-h-USP36-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human USP36 (ubiquitin specific peptidase 36). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
deubiquitinating enzyme 36; DUB1; ubiquitin carboxyl-terminal hydrolase 36; ubiquitin specific protease 36; ubiquitin thioesterase 36; ubiquitin-specific-processing protease 36
Description (eCommerce)
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 36 (USP36) is a member of this family.
Description (Vector)
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP36 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 (PubMed 14715245)).(supplied by OMIM, Jan 2009)
Gene ID
57602
Gene Name (eCommerce)
ubiquitin specific peptidase 36
Gene Name (Vector)
ubiquitin specific peptidase 36
Gene Symbol
USP36
HGNC ID
HGNC:20062
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3372
ORF Size (bp)
3372 bp
Protein Name (eCommerce)
Ubiquitin carboxyl-terminal hydrolase 36
RefSeq ID
NM_025090
RefSeq Synonyms
NM_025090, NM_001321291, BC071582, BC038983,
Research Areas
Ubiquitination
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 36 (USP36) is a member of this family.
UniGene ID
Hs.464243
UniProt ID (eCommerce)
Q9P275
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.