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human USP19 shRNA silencing Adenovirus

Name 
Ad-h-USP19-shRNA
Cat No 
shADV-227290
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human USP19.

shADV-227290
Ad-h-USP19-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human USP19 (ubiquitin specific peptidase 19). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
deubiquitinating enzyme 19; ubiquitin carboxyl-terminal hydrolase 19; ubiquitin specific protease 19; ubiquitin thioesterase 19; ubiquitin thiolesterase 19; ubiquitin-specific-processing protease 19; zinc finger MYND domain-containing protein 9; ZMYND9
Description (eCommerce)
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 19 (USP19) is a member of this family. USP19 is a 146 kDa protein that contains two CS domains and one MYND-type zinc finger.
Gene ID
10869
Gene Name (eCommerce)
ubiquitin specific peptidase 19
Gene Name (Vector)
ubiquitin specific peptidase 19
Gene Symbol
USP19
HGNC ID
HGNC:12617
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3957
ORF Size (bp)
3957 bp
Protein Name (eCommerce)
Ubiquitin carboxyl-terminal hydrolase 19
RefSeq ID
NM_006677
RefSeq Synonyms
NM_006677, NM_001199162, NM_001199161, NM_001199160, BC146752,
Research Areas
Cell Cycle,Hypoxia,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 19 (USP19) is a member of this family. USP19 is a 146 kDa protein that contains two CS domains and one MYND-type zinc finger.
UniGene ID
Hs.255596
UniProt ID (eCommerce)
O94966

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.