human UBE3C shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human UBE3C.
shADV-227051
Ad-h-UBE3C-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human UBE3C (ubiquitin protein ligase E3C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HECTH2; HECT-type ubiquitin transferase E3C; ubiquitin-protein isopeptide ligase (E3); ubiquitin-protein ligase E3C
Description (eCommerce)
Ubiquitin protein ligase E3C (UBE3C) is an E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15386].
Gene ID
9690
Gene Name (eCommerce)
ubiquitin protein ligase E3C
Gene Name (Vector)
ubiquitin protein ligase E3C
Gene Symbol
UBE3C
HGNC ID
HGNC:16803
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1950
ORF Size (bp)
1950 bp
Protein Name (eCommerce)
Ubiquitin-protein ligase E3C
RefSeq ID
NM_014671
RefSeq Synonyms
NM_014671, BC014029,
Research Areas
Antigen Processing and Presentation,Complexome,Immunology,Proteasome,Ubiquitination
Research Areas (Faceted)
cell_biology,immunology
Species
human
Target Sentence
Ubiquitin protein ligase E3C (UBE3C) is an E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15386].
UniGene ID
Hs.118351
UniProt ID (eCommerce)
Q15386
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.