human UBE2T shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human UBE2T.
shADV-227036
Ad-h-UBE2T-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human UBE2T (ubiquitin conjugating enzyme E2 T). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cell proliferation-inducing gene 50 protein; E2 ubiquitin-conjugating enzyme T; FANCT; HSPC150; HSPC150 protein similar to ubiquitin-conjugating enzyme; PIG50; ubiquitin carrier protein T; ubiquitin conjugating enzyme E2T; ubiquitin-conjugating enzyme E2 T; ubiquitin-conjugating enzyme E2T (putative); ubiquitin-protein ligase T
Description (eCommerce)
Ubiquitin-conjugating enzyme E2 T (UBE2T) is an E2 ubiquitin-conjugating enzyme that is part of the three-step pathway responsible for the covalent attachment of ubiquitin to proteins for their targeted degradation. UBET2 in conjuction with the Fanconi anemia (FA) complex is responsible for the DNA damage-induced monoubiquitination of the FANCD2 protein of the Fanconi Anemia pathway.
Description (Vector)
The covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3) (Machida et al., 2006 (PubMed 16916645)).(supplied by OMIM, Mar 2008)
Gene ID
29089
Gene Name (eCommerce)
ubiquitin conjugating enzyme E2 T
Gene Name (Vector)
ubiquitin conjugating enzyme E2 T
Gene Symbol
UBE2T
HGNC ID
HGNC:25009
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
594
Protein Name (eCommerce)
Ubiquitin-conjugating enzyme E2 T
RefSeq ID
NM_014176
RefSeq Synonyms
NM_014176, NM_001310326, BC019284, BC004152,
Research Areas
Cancer,DNA Damage/Repair,Fanconi anemia,Ubiquitination
Research Areas (Faceted)
cancer,genetics,transcription_translation,cell_biology,genetics
Species
human
Target Sentence
Ubiquitin-conjugating enzyme E2 T (UBE2T) is an E2 ubiquitin-conjugating enzyme that is part of the three-step pathway responsible for the covalent attachment of ubiquitin to proteins for their targeted degradation. UBET2 in conjuction with the Fanconi anemia (FA) complex is responsible for the DNA damage-induced monoubiquitination of the FANCD2 protein of the Fanconi Anemia pathway.
UniGene ID
Hs.5199
UniProt ID (eCommerce)
Q9NPD8
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.