human UBE2L6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human UBE2L6.
shADV-227023
Ad-h-UBE2L6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human UBE2L6 (ubiquitin conjugating enzyme E2 L6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RIG-B; UBCH8
Description (Vector)
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
9246
Gene Name (Vector)
ubiquitin conjugating enzyme E2 L6
Gene Symbol
UBE2L6
HGNC ID
HGNC:12490
ORF Size (aa)
462
RefSeq ID
NM_004223
RefSeq Synonyms
NM_198183, NM_004223, BC032491,
Species
human
UniGene ID
Hs.425777
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.