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human UBE2C shRNA silencing Adenovirus

Name 
Ad-h-UBE2C-shRNA
Cat No 
shADV-226991
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human UBE2C.

shADV-226991
Ad-h-UBE2C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human UBE2C (ubiquitin conjugating enzyme E2 C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
dJ447F3.2; UBCH10
Description (Vector)
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
11065
Gene Name (Vector)
ubiquitin conjugating enzyme E2 C
Gene Symbol
UBE2C
HGNC ID
HGNC:15937
ORF Size (aa)
540
RefSeq ID
NM_007019
RefSeq Synonyms
NM_181803, NM_181802, NM_181801, NM_181800, NM_181799, NM_007019, NM_001281742, NM_001281741, BC050736, BC016292, BC007656,
Species
human
UniGene ID
Hs.93002

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.