human TXNDC12 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TXNDC12.
shADV-226899
Ad-h-TXNDC12-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TXNDC12 (thioredoxin domain containing 12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AG1; AGR1; ERP16; ERP18; ERP19; hAG-1; hTLP19; PDIA16; TLP19
Description (Vector)
TXNDC12 encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.
Gene ID
51060
Gene Name (Vector)
thioredoxin domain containing 12
Gene Symbol
TXNDC12
HGNC ID
HGNC:24626
ORF Size (aa)
519
RefSeq ID
NM_015913
RefSeq Synonyms
NM_015913, BC008953, BC008913, BC001493,
Species
human
UniGene ID
Hs.476033
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.