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human TSHR shRNA silencing Adenovirus

Name 
Ad-h-TSHR-shRNA
Cat No 
shADV-226605
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TSHR.

shADV-226605
Ad-h-TSHR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TSHR (thyroid stimulating hormone receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CHNG1; hTSHR-I; LGR3
Description (Vector)
TSHR is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
7253
Gene Name (Vector)
thyroid stimulating hormone receptor
Gene Symbol
TSHR
HGNC ID
HGNC:12373
ORF Size (aa)
2295
ORF Size (bp)
2295 bp
RefSeq ID
NM_000369
RefSeq Synonyms
NM_001142626, NM_001018036, NM_000369, BC156779, BC063613, BC009237,
Species
human
UniGene ID
Hs.160411

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.