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human TRPM1 shRNA silencing Adenovirus

Name 
Ad-h-TRPM1-shRNA
Cat No 
shADV-226549
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TRPM1.

shADV-226549
Ad-h-TRPM1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRPM1 (transient receptor potential cation channel subfamily M member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CSNB1C; LTRPC1; MLSN1
Description (Vector)
TRPM1 encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants.
Gene ID
4308
Gene Name (Vector)
transient receptor potential cation channel subfamily M member 1
Gene Symbol
TRPM1
HGNC ID
HGNC:7146
ORF Size (aa)
4809
ORF Size (bp)
4809 bp
RefSeq ID
NM_002420
RefSeq Synonyms
NM_002420, NM_001252030, NM_001252024, NM_001252020, BC156069, BC058286,
Species
human
UniGene ID
Hs.155942

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.