human TRIM47 shRNA silencing Adenovirus

Name 
Ad-h-TRIM47-shRNA
Cat No 
shADV-226445
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TRIM47.

shADV-226445
Ad-h-TRIM47-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRIM47 (tripartite motif containing 47). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
E3 ubiquitin-protein ligase TRIM47; gene overexpressed in astrocytoma protein; GOA; RING finger protein 100; RNF100; tripartite motif-containing protein 47
Description (eCommerce)
TRIM47/GOA is a member of the tripartite motif RBCC/Trim domain family that contains a RING-finger domain, B-boxes, and an alpha-helical coiled-coil region. TRIM47/GOA was identified as a protein overexpressed in astrocytoma tumor cells and is thought to play a role in dedifferentiation associated with tumorigenesis.
Gene ID
91107
Gene Name (eCommerce)
tripartite motif containing 47
Gene Name (Vector)
tripartite motif containing 47
Gene Symbol
TRIM47
HGNC ID
HGNC:19020
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1203
ORF Size (bp)
1203 bp
Protein Name (eCommerce)
Tripartite motif-containing protein 47
RefSeq ID
NM_033452
RefSeq Synonyms
NM_033452, BC017299,
Research Areas
Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
TRIM47/GOA is a member of the tripartite motif RBCC/Trim domain family that contains a RING-finger domain, B-boxes, and an alpha-helical coiled-coil region. TRIM47/GOA was identified as a protein overexpressed in astrocytoma tumor cells and is thought to play a role in dedifferentiation associated with tumorigenesis.
UniGene ID
Hs.293660
UniProt ID (eCommerce)
Q96LD4

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.