human TRIM27 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TRIM27.
shADV-226417
Ad-h-TRIM27-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TRIM27 (tripartite motif containing 27). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RFP; RNF76
Description (Vector)
TRIM27 encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.
Gene ID
5987
Gene Name (Vector)
tripartite motif containing 27
Gene Symbol
TRIM27
HGNC ID
HGNC:9975
ORF Size (aa)
1542
ORF Size (bp)
1542 bp
RefSeq ID
NM_006510
RefSeq Synonyms
NM_006510, BC066924, BC013580,
Species
human
UniGene ID
Hs.440382
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.