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human TRIM23 shRNA silencing Adenovirus

Name 
Ad-h-TRIM23-shRNA
Cat No 
shADV-226413
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TRIM23.

shADV-226413
Ad-h-TRIM23-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRIM23 (tripartite motif containing 23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARD1; ARFD1; RNF46
Description (Vector)
TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Gene ID
373
Gene Name (Vector)
tripartite motif containing 23
Gene Symbol
TRIM23
HGNC ID
HGNC:660
ORF Size (aa)
1725
ORF Size (bp)
1725 bp
RefSeq ID
NM_001656
RefSeq Synonyms
NM_033228, NM_033227, NM_001656, BC022510,
Species
human
UniGene ID
Hs.792

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.