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human TNFRSF13C shRNA silencing Adenovirus

Name 
Ad-h-TNFRSF13C-shRNA
Cat No 
shADV-226075
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TNFRSF13C.

shADV-226075
Ad-h-TNFRSF13C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TNFRSF13C (TNF receptor superfamily member 13C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BAFF-R; BAFFR; BROMIX; CD268; CVID4; prolixin
Description (Vector)
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Gene ID
115650
Gene Name (Vector)
TNF receptor superfamily member 13C
Gene Symbol
TNFRSF13C
HGNC ID
HGNC:17755
ORF Size (aa)
555
ORF Size (bp)
555 bp
RefSeq ID
NM_052945
RefSeq Synonyms
NM_052945, BC112030, BC111585, BC105123,
Species
human
UniGene ID
Hs.344088

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.