human TNFRSF11B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TNFRSF11B.
shADV-226072
Ad-h-TNFRSF11B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TNFRSF11B (TNF receptor superfamily member 11b). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
OCIF; OPG; PDB5; TR1
Description (Vector)
TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Gene ID
4982
Gene Name (Vector)
TNF receptor superfamily member 11b
Gene Symbol
TNFRSF11B
HGNC ID
HGNC:11909
ORF Size (aa)
1206
RefSeq ID
NM_002546
RefSeq Synonyms
NM_002546, BC030155,
Species
human
UniGene ID
Hs.81791
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.