human TNFAIP6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TNFAIP6.
shADV-226061
Ad-h-TNFAIP6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TNFAIP6 (TNF alpha induced protein 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TSG-6; TSG6
Description (Vector)
TNFAIP6 is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
Gene ID
7130
Gene Name (Vector)
TNF alpha induced protein 6
Gene Symbol
TNFAIP6
HGNC ID
HGNC:11898
ORF Size (aa)
834
RefSeq ID
NM_007115
RefSeq Synonyms
NM_007115, BC030205,
Species
human
UniGene ID
Hs.437322
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.