human TMPRSS3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TMPRSS3.
shADV-226014
Ad-h-TMPRSS3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TMPRSS3 (transmembrane protease, serine 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DFNB10; DFNB8; ECHOS1; TADG12
Description (Vector)
TMPRSS3 encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. TMPRSS3 was identified by its association with both congenital and childhood onset autosomal recessive deafness. TMPRSS3 is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. TMPRSS3 was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
Gene ID
64699
Gene Name (Vector)
transmembrane protease, serine 3
Gene Symbol
TMPRSS3
HGNC ID
HGNC:11877
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_024022
RefSeq Synonyms
NM_032405, NM_032404, NM_024022, NM_001256317, BC074847, BC074846,
Species
human
UniGene ID
Hs.208600
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.