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human TGFBR3 shRNA silencing Adenovirus

Name 
Ad-h-TGFBR3-shRNA
Cat No 
shADV-225392
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TGFBR3.

shADV-225392
Ad-h-TGFBR3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TGFBR3 (transforming growth factor beta receptor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
betaglycan; BGCAN
Description (Vector)
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene ID
7049
Gene Name (Vector)
transforming growth factor beta receptor 3
Gene Symbol
TGFBR3
HGNC ID
HGNC:11774
ORF Size (aa)
2556
ORF Size (bp)
2556 bp
RefSeq ID
NM_003243
RefSeq Synonyms
NM_003243, NM_001195684, NM_001195683, BC136295, BC126116,
Species
human
UniGene ID
Hs.482390

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.