human TFB1M shRNA silencing Adenovirus

Name 
Ad-h-TFB1M-shRNA
Cat No 
shADV-225351
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TFB1M.

shADV-225351
Ad-h-TFB1M-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TFB1M (transcription factor B1, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CGI-75; CGI75; mtTFB; mtTFB1
Description (Vector)
TFB1M is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).
Gene ID
51106
Gene Name (Vector)
transcription factor B1, mitochondrial
Gene Symbol
TFB1M
HGNC ID
HGNC:17037
ORF Size (aa)
1041
RefSeq ID
NM_016020
RefSeq Synonyms
NM_016020, BC017788,
Species
human
UniGene ID
Hs.279908

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.