human TECTA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TECTA.
shADV-225292
Ad-h-TECTA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TECTA (tectorin alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DFNA12; DFNA8; DFNB21
Description (Vector)
The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness.
Gene ID
7007
Gene Name (Vector)
tectorin alpha
Gene Symbol
TECTA
HGNC ID
HGNC:11720
ORF Size (aa)
6465
ORF Size (bp)
6465 bp
RefSeq ID
NM_005422
RefSeq Synonyms
NM_005422, BC172509, BC156465,
Species
human
UniGene ID
Hs.248162
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.