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human TBL2 shRNA silencing Adenovirus

Name 
Ad-h-TBL2-shRNA
Cat No 
shADV-225134
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TBL2.

shADV-225134
Ad-h-TBL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TBL2 (transducin beta like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; transducin beta-like protein 2; transducin -like 2; WBSCR13; Williams-Beuren syndrome chromosomal region 13 protein; Williams-Beuren syndrome chromosome region 13; WS beta-transducin repeats protein; WS-betaTRP
Description (eCommerce)
Transducin beta-like protein 2, a member of the beta-transducin protein family is encoded by the gene TBL2. Most proteins of the beta-transducin family are involved in regulatory functions. This gene is deleted in Williams-Beuren syndrome [taken from NCBI Entrez Gene (Gene ID: 26608)].
Description (Vector)
TBL2 encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. TBL2 is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
Gene ID
26608
Gene Name (eCommerce)
transducin beta like 2
Gene Name (Vector)
transducin beta like 2
Gene Symbol
TBL2
HGNC ID
HGNC:11586
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1341
ORF Size (bp)
1341 bp
Protein Name (eCommerce)
Transducin beta-like protein 2
RefSeq ID
NM_012453
RefSeq Synonyms
NM_012453, BC012938,
Research Areas
Neurobiology
Research Areas (Faceted)
neurobiology
Species
human
Target Sentence
Transducin beta-like protein 2, a member of the beta-transducin protein family is encoded by the gene TBL2. Most proteins of the beta-transducin family are involved in regulatory functions. This gene is deleted in Williams-Beuren syndrome [taken from NCBI Entrez Gene (Gene ID: 26608)].
UniGene ID
Hs.647044
UniProt ID (eCommerce)
Q9Y4P3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.