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human TBC1D10C shRNA silencing Adenovirus

Name 
Ad-h-TBC1D10C-shRNA
Cat No 
shADV-225064
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TBC1D10C.

shADV-225064
Ad-h-TBC1D10C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TBC1D10C (TBC1 domain family member 10C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CARABIN; EPI64C
Description (Vector)
TBC1D10C has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromsomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
374403
Gene Name (Vector)
TBC1 domain family member 10C
Gene Symbol
TBC1D10C
HGNC ID
HGNC:24702
ORF Size (aa)
1341
ORF Size (bp)
1341 bp
RefSeq ID
NM_198517
RefSeq Synonyms
NM_198517, NM_001256508, BC062999, BC036873,
Species
human
UniGene ID
Hs.534648

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.