human TAP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TAP1.
shADV-224966
Ad-h-TAP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TAP1 (transporter 1, ATP binding cassette subfamily B member). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABC17; ABCB2; APT1; D6S114E; PSF-1; PSF1; RING4; TAP1*0102N; TAP1N
Description (Vector)
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.
Gene ID
6890
Gene Name (Vector)
transporter 1, ATP binding cassette subfamily B member
Gene Symbol
TAP1
HGNC ID
HGNC:43
ORF Size (aa)
2427
ORF Size (bp)
2427 bp
RefSeq ID
NM_000593
RefSeq Synonyms
NM_001292022, NM_000593, BC014081,
Species
human
UniGene ID
Hs.352018
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.