human MAP4K5 Over-expression AAV

Name 
AAV-h-MAP4K5
Cat No 
AAV-214954
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MAP4K5.

AAV-214954
AAV-h-MAP4K5

Ready-to-use AAV expressing Human MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GCKR; KHS; KHS1; MAPKKKK5
Description (Vector)
MAP4K5 encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Gene ID
11183
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase kinase 5
Gene Symbol
MAP4K5
HGNC ID
HGNC:6867
ORF Size (aa)
2541
ORF Size (bp)
2541 bp
RefSeq ID
NM_006575
RefSeq Synonyms
NM_198794, NM_006575, BC036013,
Species
human
UniGene ID
Hs.130491

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.