human TAF12 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TAF12.
shADV-224912
Ad-h-TAF12-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TAF12 (TATA-box binding protein associated factor 12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TAF2J; TAFII20
Description (Vector)
Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
6883
Gene Name (Vector)
TATA-box binding protein associated factor 12
Gene Symbol
TAF12
HGNC ID
HGNC:11545
ORF Size (aa)
486
ORF Size (bp)
486 bp
RefSeq ID
NM_005644
RefSeq Synonyms
NM_005644, NM_001135218, BC011986,
Species
human
UniGene ID
Hs.530251
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.