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human SYT12 shRNA silencing Adenovirus

Name 
Ad-h-SYT12-shRNA
Cat No 
shADV-224842
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SYT12.

shADV-224842
Ad-h-SYT12-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SYT12 (synaptotagmin 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SYT11; sytXII
Description (Vector)
SYT12 is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
Gene ID
91683
Gene Name (Vector)
synaptotagmin 12
Gene Symbol
SYT12
HGNC ID
HGNC:18381
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
RefSeq ID
NM_177963
RefSeq Synonyms
NM_177963, NM_001318775, NM_001318773, NM_001177880, BC037406,
Species
human
UniGene ID
Hs.287636

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.