human SYN2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SYN2.
shADV-224804
Ad-h-SYN2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SYN2 (synapsin II). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SYNII
Description (Vector)
SYN2 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts.
Gene ID
6854
Gene Name (Vector)
synapsin II
Gene Symbol
SYN2
HGNC ID
HGNC:11495
ORF Size (aa)
1749
ORF Size (bp)
1749 bp
RefSeq ID
NM_003178
RefSeq Synonyms
NM_133625, NM_003178, BC051307,
Species
human
UniGene ID
Hs.445503
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.