human SURF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SURF1.
shADV-224757
Ad-h-SURF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SURF1 (SURF1, cytochrome c oxidase assembly factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMT4K
Description (Vector)
SURF1 encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Gene ID
6834
Gene Name (Vector)
SURF1, cytochrome c oxidase assembly factor
Gene Symbol
SURF1
HGNC ID
HGNC:11474
ORF Size (aa)
903
RefSeq ID
NM_003172
RefSeq Synonyms
NM_003172, NM_001280787, BC071658, BC028314,
Species
human
UniGene ID
Hs.512464
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.