human SUCLG1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SUCLG1.
shADV-224693
Ad-h-SUCLG1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SUCLG1 (succinate-CoA ligase alpha subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GALPHA; MTDPS9; SCS-alpha; succinate--CoA ligase ADP/GDP-forming subunit alpha, mitochondrial; succinyl-CoA ligase ADP/GDP-forming subunit alpha, mitochondrial; succinyl-CoA ligase GDP-forming subunit alpha, mitochondrial; succinyl-CoA synthetase subunit alpha; SUCLA1
Description (eCommerce)
SUCLG1 is the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP [taken from NCBI Entrez Gene (Gene ID: 8802)].
Description (Vector)
SUCLG1 encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.
Gene ID
8802
Gene Name (eCommerce)
succinate-CoA ligase alpha subunit
Gene Name (Vector)
succinate-CoA ligase alpha subunit
Gene Symbol
SUCLG1
HGNC ID
HGNC:11449
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1002
Protein Name (eCommerce)
Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
RefSeq ID
NM_003849
RefSeq Synonyms
NM_003849, BC000504,
Research Areas
Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
SUCLG1 is the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP [taken from NCBI Entrez Gene (Gene ID: 8802)].
UniGene ID
Hs.270428
UniProt ID (eCommerce)
P53597
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.