human STX1A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human STX1A.
shADV-224660
Ad-h-STX1A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human STX1A (syntaxin 1A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HPC-1; P35-1; STX1; SYN1A
Description (Vector)
STX1A encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE (Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor) domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. STX1A product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
6804
Gene Name (Vector)
syntaxin 1A
Gene Symbol
STX1A
HGNC ID
HGNC:11433
ORF Size (aa)
756
RefSeq ID
NM_004603
RefSeq Synonyms
NM_004603, NM_001165903, BC064644, BC003011,
Species
human
UniGene ID
Hs.647024
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.