human STK36 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human STK36.
shADV-224597
Ad-h-STK36-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human STK36 (serine/threonine kinase 36). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FU
Description (Vector)
STK36 encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants.
Gene ID
27148
Gene Name (Vector)
serine/threonine kinase 36
Gene Symbol
STK36
HGNC ID
HGNC:17209
ORF Size (aa)
3948
ORF Size (bp)
3948 bp
RefSeq ID
NM_015690
RefSeq Synonyms
NM_015690, NM_001243313, BC026158,
Species
human
UniGene ID
Hs.712986
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.