human ST3GAL5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ST3GAL5.
shADV-224461
Ad-h-ST3GAL5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SATI; SIAT9; SIATGM3S; SPDRS; ST3GalV
Description (Vector)
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.
Gene ID
8869
Gene Name (Vector)
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
Gene Symbol
ST3GAL5
HGNC ID
HGNC:10872
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
RefSeq ID
NM_003896
RefSeq Synonyms
NM_003896, NM_001042437, BC065936,
Species
human
UniGene ID
Hs.415117
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.