human SRC shRNA silencing Adenovirus

Name 
Ad-h-SRC-shRNA
Cat No 
shADV-224308
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SRC.

shADV-224308
Ad-h-SRC-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SRC (SRC proto-oncogene, non-receptor tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ASV; c-SRC; p60-Src; SRC1; THC6
Description (Vector)
SRC is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
6714
Gene Name (Vector)
SRC proto-oncogene, non-receptor tyrosine kinase
Gene Symbol
SRC
HGNC ID
HGNC:11283
ORF Size (aa)
1611
ORF Size (bp)
1611 bp
RefSeq ID
NM_198291
RefSeq Synonyms
NM_198291, NM_005417, BC051270, BC011566,
Species
human
UniGene ID
Hs.195659

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.