human SPG7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SPG7.
shADV-224163
Ad-h-SPG7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SPG7 (SPG7, paraplegin matrix AAA peptidase subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAR; CMAR; PGN; SPG5C
Description (Vector)
SPG7 encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7.
Gene ID
6687
Gene Name (Vector)
SPG7, paraplegin matrix AAA peptidase subunit
Gene Symbol
SPG7
HGNC ID
HGNC:11237
ORF Size (aa)
2388
ORF Size (bp)
2388 bp
RefSeq ID
NM_003119
RefSeq Synonyms
NM_199367, NM_003119, BC036104, BC007692,
Species
human
UniGene ID
Hs.185597
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.