human SPCS1 shRNA silencing Adenovirus

Name 
Ad-h-SPCS1-shRNA
Cat No 
shADV-224135
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SPCS1.

shADV-224135
Ad-h-SPCS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SPCS1 (signal peptidase complex subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HSPC033; microsomal signal peptidase 12 kDa subunit; signal peptidase 12kDa; signal peptidase complex 12 kDa subunit; signal peptidase complex subunit 1; signal peptidase complex subunit 1 homolog; SPase 12 kDa subunit; SPC1; SPC12; YJR010C-A
Description (eCommerce)
SPCS1 is a component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6A9].
Gene ID
28972
Gene Name (eCommerce)
signal peptidase complex subunit 1
Gene Name (Vector)
signal peptidase complex subunit 1
Gene Symbol
SPCS1
HGNC ID
HGNC:23401
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
315
ORF Size (bp)
315 bp
Protein Name (eCommerce)
Signal peptidase complex subunit 1
RefSeq ID
NM_014041
RefSeq Synonyms
NM_014041, BC000884,
Research Areas
Gene Expression,Metabolism/Metabolic Process,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
SPCS1 is a component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6A9].
UniGene ID
Hs.11125
UniProt ID (eCommerce)
Q9Y6A9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.