human SOCS6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SOCS6.
shADV-223978
Ad-h-SOCS6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SOCS6 (suppressor of cytokine signaling 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CIS-4; CIS4; HSPC060; SOCS-4; SOCS-6; SOCS4; SSI4; STAI4; STATI4
Description (Vector)
SOCS6 contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Gene ID
9306
Gene Name (Vector)
suppressor of cytokine signaling 6
Gene Symbol
SOCS6
HGNC ID
HGNC:16833
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
RefSeq ID
NM_004232
RefSeq Synonyms
NM_004232, BC020082,
Species
human
UniGene ID
Hs.44439
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.