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human SNX27 shRNA silencing Adenovirus

Name 
Ad-h-SNX27-shRNA
Cat No 
shADV-223943
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SNX27.

shADV-223943
Ad-h-SNX27-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SNX27 (sorting nexin family member 27). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
methamphetamine-responsive transcript 1; MRT1; MY014; sorting nexin-27
Description (eCommerce)
Sorting nexin-27 (SNX27) is a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein [taken from NCBI Entrez Gene (Gene ID: 81609)].
Description (Vector)
SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.
Gene ID
81609
Gene Name (eCommerce)
sorting nexin family member 27
Gene Name (Vector)
sorting nexin family member 27
Gene Symbol
SNX27
HGNC ID
HGNC:20073
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1587
ORF Size (bp)
1587 bp
Protein Name (eCommerce)
Sorting nexin-27
RefSeq ID
NM_030918
RefSeq Synonyms
NM_030918, NM_001330723, BC101824, BC101822, BC101000, BC100999, BC100998, BC012184,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Sorting nexin-27 (SNX27) is a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein [taken from NCBI Entrez Gene (Gene ID: 81609)].
UniGene ID
Hs.192326
UniProt ID (eCommerce)
Q96L92

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.