human SNTB1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SNTB1.
shADV-223904
Ad-h-SNTB1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SNTB1 (syntrophin beta 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
59 kDa dystrophin-associated protein A1 basic component 1; 59-DAP; A1B; beta-1-syntrophin; BSYN2; DAPA1B; dystrophin-associated protein A1, 59kD, basic component 1; SNT2; SNT2B1; syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1); syntrophin-2; tax interaction protein 43; TIP-43
Description (eCommerce)
Syntrophin-1 is an adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. It may link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13884].
Description (Vector)
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
Gene ID
6641
Gene Name (eCommerce)
syntrophin beta 1
Gene Name (Vector)
syntrophin beta 1
Gene Symbol
SNTB1
HGNC ID
HGNC:11168
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1617
ORF Size (bp)
1617 bp
Protein Name (eCommerce)
Beta-1-syntrophin
RefSeq ID
NM_021021
RefSeq Synonyms
NM_021021, BC098573,
Research Areas
Cardiology,Cardiovascular,Cytoskeleton,Neurobiology,Synapse
Research Areas (Faceted)
cardiovascular,cell_biology,neurobiology
Species
human
Target Sentence
Syntrophin-1 is an adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. It may link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13884].
UniGene ID
Hs.46701
UniProt ID (eCommerce)
Q13884
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.