human MAGMAS Over-expression AAV

Name 
AAV-h-MAGMAS
Cat No 
AAV-214850
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PAM16.

AAV-214850
AAV-h-MAGMAS

Ready-to-use AAV expressing Human PAM16 (presequence translocase associated motor 16 homolog). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CGI-136; MAGMAS; magmas-like protein; mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction; mitochondria-associated granulocyte macrophage CSF-signaling molecule; mitochondrial import inner membrane translocase subunit TIM16; presequence translocase associated motor 16 homolog; Presequence translocated-associated motor subunit PAM16; SMDMDM; TIM16; TIMM16
Description (eCommerce)
PAM16 regulates ATP-dependent protein translocation into the mitochondrial matrix.It inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3D7].
Gene ID
51025
Gene Name (eCommerce)
presequence translocase associated motor 16
Gene Name (Vector)
presequence translocase associated motor 16 homolog
Gene Symbol
PAM16
HGNC ID
HGNC:29679
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
378
ORF Size (bp)
378 bp
Protein Name (eCommerce)
Mitochondrial import inner membrane translocase subunit TIM16
RefSeq ID
NM_016069
RefSeq Synonyms
NM_016069, BC005024,
Research Areas
Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
PAM16 regulates ATP-dependent protein translocation into the mitochondrial matrix.It inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3D7].
UniGene ID
Hs.644614
UniProt ID (eCommerce)
Q9Y3D7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.