human SLC26A5 shRNA silencing Adenovirus

Name 
Ad-h-SLC26A5-shRNA
Cat No 
shADV-223306
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SLC26A5.

shADV-223306
Ad-h-SLC26A5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SLC26A5 (solute carrier family 26 member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DFNB61; PRES
Description (Vector)
SLC26A5 encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
375611
Gene Name (Vector)
solute carrier family 26 member 5
Gene Symbol
SLC26A5
HGNC ID
HGNC:9359
ORF Size (aa)
2139
ORF Size (bp)
2139 bp
RefSeq ID
NM_198999
RefSeq Synonyms
NM_206885, NM_206884, NM_206883, NM_198999, NM_001321787, NM_001167962, BC100835, BC100833, BC100832,
Species
human
UniGene ID
Hs.585146

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.