human SLC12A5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SLC12A5.
shADV-223089
Ad-h-SLC12A5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SLC12A5 (solute carrier family 12 member 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EIEE34; EIG14; hKCC2; KCC2
Description (Vector)
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms.
Gene ID
57468
Gene Name (Vector)
solute carrier family 12 member 5
Gene Symbol
SLC12A5
HGNC ID
HGNC:13818
ORF Size (aa)
3351
ORF Size (bp)
3351 bp
RefSeq ID
NM_020708
RefSeq Synonyms
NM_020708, NM_001134771, BC132670, BC132668,
Species
human
UniGene ID
Hs.21413
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.