human SIRT5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SIRT5.
shADV-223020
Ad-h-SIRT5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SIRT5 (sirtuin 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SIR2L5
Description (Vector)
SIRT5 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
Gene ID
23408
Gene Name (Vector)
sirtuin 5
Gene Symbol
SIRT5
HGNC ID
HGNC:14933
ORF Size (aa)
933
RefSeq ID
NM_012241
RefSeq Synonyms
NM_031244, NM_012241, NM_001242827, NM_001193267, BC000126,
Species
human
UniGene ID
Hs.594133
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.