human SIM1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SIM1.
shADV-223003
Ad-h-SIM1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SIM1 (single-minded family bHLH transcription factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHe14
Description (Vector)
SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.
Gene ID
6492
Gene Name (Vector)
single-minded family bHLH transcription factor 1
Gene Symbol
SIM1
HGNC ID
HGNC:10882
ORF Size (aa)
2298
ORF Size (bp)
2298 bp
RefSeq ID
NM_005068
RefSeq Synonyms
NM_005068, BC118500, BC111931,
Species
human
UniGene ID
Hs.520293
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.