human SHCBP1 shRNA silencing Adenovirus

Name 
Ad-h-SHCBP1-shRNA
Cat No 
shADV-222935
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SHCBP1.

shADV-222935
Ad-h-SHCBP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SHCBP1 (SHC binding and spindle associated 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PAL; Protein expressed in Activated Lymphocytes; SHC SH2 domain-binding protein 1
Description (eCommerce)
SHC SH2 domain-binding protein 1 (SHCBP1) may play a role in signaling pathways governing cellular proliferation, cell growth, and differentiation. SHCBP1 may be a component of a novel signaling pathway downstream of Shc. SHCBP1 acts as a positive regulator of FGF signaling in neural progenitor cells (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NEM2].
Gene ID
79801
Gene Name (eCommerce)
SHC binding and spindle associated 1
Gene Name (Vector)
SHC binding and spindle associated 1
Gene Symbol
SHCBP1
HGNC ID
HGNC:29547
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2019
ORF Size (bp)
2019 bp
Protein Name (eCommerce)
SHC SH2 domain-binding protein 1
RefSeq ID
NM_024745
RefSeq Synonyms
NM_024745, NM_001324319, NM_001324318, BC030699,
Research Areas
FGF Signaling,Neurobiology,Neurodevelopment,Signal Transduction
Research Areas (Faceted)
signal_transduction,developmental_biology,neurobiology,developmental_biology
Species
human
Target Sentence
SHC SH2 domain-binding protein 1 (SHCBP1) may play a role in signaling pathways governing cellular proliferation, cell growth, and differentiation. SHCBP1 may be a component of a novel signaling pathway downstream of Shc. SHCBP1 acts as a positive regulator of FGF signaling in neural progenitor cells (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NEM2].
UniGene ID
Hs.123253
UniProt ID (eCommerce)
Q8NEM2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.