human SGCZ shRNA silencing Adenovirus

Name
Ad-h-SGCZ-shRNA

Cat No
shADV-222847

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human SGCZ.

shADV-222847

Ad-h-SGCZ-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SGCZ (sarcoglycan zeta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ZSG1

Description (Vector)

The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.

Gene ID

137868

Gene Name (Vector)

sarcoglycan zeta

Gene Symbol

SGCZ

HGNC ID

HGNC:14075

ORF Size (aa)

798

RefSeq ID

NM_139167

RefSeq Synonyms

NM_139167, NM_001322881, NM_001322880, NM_001322879, BC125037,

Species

human

UniGene ID

Hs.676196

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.