human SFRS8 shRNA silencing Adenovirus

Name 
Ad-h-SFRS8-shRNA
Cat No 
shADV-222817
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SFSWAP.

shADV-222817
Ad-h-SFRS8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SFSWAP (splicing factor SWAP homolog). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SFRS8; splicing factor SWAP homolog; Splicing factor, arginine/serine-rich 8; splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila); splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot, Drosophila homolog); splicing factor, suppressor of white-apricot family; splicing factor, suppressor of white-apricot homolog; suppressor of white apricot protein homolog; SWAP
Description (eCommerce)
SFRS8 is the human homolog of the drosophila splicing regulatory protein SWAP (suppressor of white apricot). SFRS2IP contains an arginine-serine-rich (RS) domain and has been shown to regulate the splicing of itself as well as fibronectin and CD45.
Description (Vector)
SFSWAP encodes a human homolog of Drosophila splicing regulatory protein. SFSWAP autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified.
Gene ID
6433
Gene Name (eCommerce)
splicing factor SWAP
Gene Name (Vector)
splicing factor SWAP homolog
Gene Symbol
SFSWAP
HGNC ID
HGNC:10790
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3012
ORF Size (bp)
3012 bp
Protein Name (eCommerce)
Splicing factor, suppressor of white-apricot homolog
RefSeq ID
NM_004592
RefSeq Synonyms
NM_004592, NM_001261411, BC144364, BC136678,
Research Areas
mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
SFRS8 is the human homolog of the drosophila splicing regulatory protein SWAP (suppressor of white apricot). SFRS2IP contains an arginine-serine-rich (RS) domain and has been shown to regulate the splicing of itself as well as fibronectin and CD45.
UniGene ID
Hs.308171
UniProt ID (eCommerce)
Q12872

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.